Please help me stop being a clicker.

I know its terrible, its shameful even, especially considering I have been playing World of Warcraft since the classic Beta but I just never got around to doing it. I always said to myself I'll start using binds next week, and week after week I kept looking at the keyboard like it was the elephant in the room.

Well no more! I actually want to be good at the game for a change, and after recently upgrading to a new computer I splashed out and got a nice Razer keyboard and mouse. The mouse is a 12 button Naga so I can hopefully avoid too many keyboard binds but I really need help getting started.

It feels very unnatural to me to use keyboard binds, I don't really know why. My typing speed is above average as I use a keyboard for work everyday so its not that I am against effort, but I do need a little help figuring out the best binds to start off with.

At the moment I have assigned these abilities to my mouse:

1: Mortal Strike
2: Overpower
3:Slam
4: Pummell
5:Colossus Smash
6: Charge

I have 6 more buttons on the mouse however it doesn't really feel that comfortable to press, it requires me bending my thumb in an unnatural way, ideally I would like to stick to these 6 buttons on the mouse for now, perhaps use number 7 as well and to a lesser extent number 10.

My question is how have you guys set up your keyboards to compensate for the other spells, what do you find natural, what can I get away without binding?

Any help would be much appreciated and I look forwards to peoples ideas.

Thanks.